Beckwith-Wiedemann Syndrome in a patient with full-term pregnancy, case report

Abstract

Beckwith-Wiedemann Syndrome (BWS) is a rare congenital disorder caused by alterations to the IGF2 gene. Its incidence has increased with the use of assisted reproduction techniques. We present a case of a patient with BWS who experienced anaphylactic shock during delivery, likely related to oxytocin use. Multidisciplinary management is necessary in cases of prenatal diagnosis, with a focus on early correction of hypoglycemia and structural defects. BWS is associated with an increased risk of childhood cancer, and the use of assisted reproduction techniques may further increase this risk. Clinicians should be aware of the potential complications associated with BWS in pregnant patients and their newborns.