Disorders affecting endometrial receptivity

Abstract

Uterine receptivity is the ability of the endometrium to allow normal embryo implantation. Abnormal uterine receptivity leads to a range of reproductive problems, from infertility or defective implantation (miscarriage) to recurrent implantation failure after IVF procedures. The best management for our couples would be to identify in advance the possible disorders that could lead to implantation failure.

Most uterine malformations and acquired abnormalities of the uterine cavity are relevant to reproductive outcomes. However, the impact of some abnormalities remains controversial, such as adenomyosis and chronic endometritis.

External factors can also affect the receptivity of the endometrium, even if they are not located inside the uterine cavity. The possible effects of endometriosis, hydrosalpinx and obesity are factors to consider when considering assisted reproductive technology.